NIH-funded researchers show possible trigger for MS nerve damage — Results of study in mice may lead to new treatments – High-resolution real-time images show in mice how nerves may be damaged during the earliest stages of multiple sclerosis. The results suggest that the critical step happens when fibrinogen, a blood-clotting protein, leaks into the central nervous system and activates immune cells called microglia.
Chewing ability linked to reduced dementia risk — Can you bite into an apple? If so, you are more likely to maintain mental abilities. – Can you bite into an apple? If so, you are more likely to maintain mental abilities, according to new research from Karolinska Institutet. The population is ageing, and the older we become the more likely it is that we risk deterioration of our cognitive functions, such as memory, decision-making and problem solving.
Midlife fitness staves off chronic disease at end of life, UT Southwestern researchers report — Fitness at 50 – free from chronic illness – Being physically fit during your 30s, 40s, and 50s not only helps extend lifespan, but it also increases the chances of aging healthily, free from chronic illness. For decades, research has shown that higher cardiorespiratory fitness levels lessen the risk of death, but it previously had been unknown just how much fitness might affect the burden of chronic disease in the most senior years ? a concept known as morbidity compression.
Researchers discover new mechanism behind resistance to cancer treatment — Finding could lead to development of better therapies to cure cancer – Developing resistance to chemotherapy is a nearly universal, ultimately lethal consequence for cancer patients with solid tumors ? such as those of the breast, prostate, lung and colon ? that have metastasized, or spread, throughout the body.
First detailed timeline established for brain’s descent into Alzheimer’s – Scientists have assembled the most detailed chronology to date of the human brain’s long, slow slide into full-blown Alzheimer’s disease. As part of an international research partnership known as the Dominantly Inherited Alzheimer’s Network (DIAN), scientists at Washington University and elsewhere evaluated a variety of pre-symptomatic markers of Alzheimer’s disease in 128 subjects from families genetically predisposed to develop the disorder.
Severe reactions to food more common than thought in young children — Study identifies causes for high rates of allergic reactions in children with food allergies – Young children with allergies to milk and egg experience reactions to these and other foods more often than researchers had expected. A new study found that severe and potentially life-threatening reactions in a significant number of these children occur and that some caregivers are hesitant to give such children epinephrine, a medication that reverses the symptoms of such reactions and can save lives.
New screening technique could provide more reliable breast cancer detection — Initial tests show promising results of new ultrasonic screening technique – Scientists have successfully completed an initial trial of a new, potentially more reliable, technique for screening breast cancer using ultrasound. The team at the National Physical Laboratory (NPL), the UK’s National Measurement Institute, working with the University Hospitals Bristol NHS Foundation Trust, are now looking to develop the technique into a clinical device.
Lifelong brain-stimulating habits linked to lower Alzheimer’s protein levels – Individuals who keep their brains active throughout life with cognitively stimulating activities such as reading, writing and playing games appear to have reduced levels of the ?-amyloid protein, which is the major part of the amyloid plaque in Alzheimer disease.
Cognitive Decline in Patients with Parkinson Disease Associated With Certain Patterns of Brain Volume Decreases – Patients with Parkinson disease-related dementia appear to have increased brain atrophy in the hippocampal, temporal and parietal lobes and decreased prefrontal cortex volume compared to patients with Parkinson disease without dementia.
Functional brain pathways disrupted in children with ADHD – Some abnormalities in the brains of children with attention deficit/hyperactivity disorder (ADHD) may serve as a biomarker for the disorder, according to a study presented at the annual meeting of the Radiological Society of North America (RSNA).
