Breast cancer relapse risk low after 5 years

Women who survive five years after being diagnosed with breast cancer and after adjuvant systemic therapy have a good chance of remaining cancer free. – Breast cancer survivors continue to have a substantial risk of disease recurrence after five years of systemic therapy, according to a study published in the August 12 online issue of the Journal of the National Cancer Institute.

Breast cancer spread stopped by bone drug

Maintaining bone density could be a key to decreasing the spread of cancer in women with locally advanced breast cancer. Bones are common sites for the spread, or metastasis, of breast cancer. – Researchers at Washington University School of Medicine in St. Louis found that women treated for stage II/III breast cancer who also received a bone strengthening drug zoledronic acid were less likely to have breast tumor cells growing in their bones after three months.

Fasting for 2 days protects healthy cells against chemotherapy

Fasting for two days protects healthy cells against chemotherapy, according to a study appearing online the week of March 31 in PNAS Early Edition. – Fasting for two days protects healthy cells against chemotherapy, according to a study appearing online the week of March 31 in PNAS Early Edition. Test tube experiments with human cells confirmed the differential resistance of normal and cancer cells to chemotherapy after a short period of starvation.

Lower heart effects from Herceptin breast cancer treatment with chemotherapy

Cardiac effects associated with breast cancer treatment appear lower with dose-dense delivery of conventional chemotherapy – A new pilot study by investigators at Memorial Sloan-Kettering Cancer Center (MSKCC) found that breast cancer patients can be treated safely with a “dose-dense” regimen of standard chemotherapy agents and the antibody trastuzumab (Herceptin), a drug that has previously been shown to cause cardiac toxicity.

Zebrafish offer useful screening tool for genes, drugs that protect against hearing loss

A small striped fish is helping scientists understand what makes people susceptible to a common form of hearing loss, although, in this case, it?s not the fish?s ears that are of interest. – A small striped fish is helping scientists understand what makes people susceptible to a common form of hearing loss, although, in this case, it’s not the fish’s ears that are of interest. In a study published in the Feb. 29 issue of the journal PLoS Genetics, researchers at the University of Washington have developed a research method that relies on a zebrafish’s lateral line-the faint line running down each side of a fish that enables it to sense its surroundings-to quickly screen for genes and chemical compounds that protect against hearing loss from some medications.

Race differences affect response to drugs and infections

Gene expression differences between those of European and African ancestry affect response to drugs and infections. – Differences in gene expression levels between people of European versus African ancestry can affect how each group responds to certain drugs or fights off specific infections, report researchers from the University of Chicago Medical Center and the Expression Research Laboratory at Affymetrix Inc. of Santa Clara, CA.

Genentech’s Avastin with chemotherapy approved for advanced breast cancer

FDA grants accelerated approval of Avastin in combination with Paclitaxel Chemotherapy for first-line treatment of advanced HER2-negative breast cancer. – Genentech, Inc. (NYSE: DNA) announced that the U.S. Food and Drug Administration (FDA) granted accelerated approval for Avastin (bevacizumab), in combination with paclitaxel chemotherapy, for the treatment of patients who have not received chemotherapy for their metastatic HER2-negative breast cancer.

Copper inhibits transmission of hiv through breast milk and blood

Researchers have developed an inexpensive copper-based filter that may prevent HIV from being passed through breast milk and blood. – Researchers from the U.S. and abroad have developed an inexpensive copper-based filter that may prevent HIV from being passed through breast milk and blood. They report their findings in the February 2008 issue of the journal Antimicrobial Agents and Chemotherapy.

Gene changes after smoking affects lung cancer

Smoking?s effects on genes may play a role in lung cancer development and survival; changes in gene expression persisted in people who had quit smoking many years earlier. – Smoking plays a role in lung cancer development, and now scientists have shown that smoking also affects the way genes are expressed, leading to alterations in cell division and regulation of immune response. Notably, some of the changes in gene expression persisted in people who had quit smoking many years earlier.

Zydus Cadila introduces Nudoxa cancer drug

Zydus Cadila introduces Nudoxa cancer drug

Zydus Cadila has introduced Nudoxa for the treatment of various cancers. One of the critical drugs used in chemotherapy, Nudoxa heralds a new approach in cancer therapy. – Zydus Cadila has introduced an NDDS product ‘Nudoxa’ for the treatment of various cancers. One of the critical drugs used in chemotherapy, Nudoxa heralds a new approach in cancer therapy.

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