Cleveland Clinic researcher reports that evacetrapib can increase HDL (good) cholesterol 128 percent – Researchers at Cleveland Clinic reported that administration of a new drug? evacetrapib ? can dramatically increase HDL (good) cholesterol, while significantly lowering LDL (bad) cholesterol). At the highest tested dosage, the levels of HDL more than doubled.
Intensive-Dose Statin Therapy Associated With Increased Risk of Diabetes – Use of intensive-dose statin therapy compared with moderate-dose statin therapy was associated with a higher incidence of new-onset diabetes. An analysis of data from previously published studies indicates that intensive-dose statin therapy is associated with an increased risk of new-onset diabetes compared with moderate-dose therapy, according to a study in the recent issue of JAMA.
FDA announces new safety recommendations for high-dose simvastatin — Increased risk of muscle injury cited – Patients taking simvastatin 80 mg daily had an increased risk of muscle injury. The risk of muscle injury is highest during the first year of treatment with the 80 mg dose of simvastatin, and is frequently associated with a genetic predisposition for simvastatin-related muscle injury or myopathy.
Super-sticky ‘ultra-bad’ cholesterol revealed in people at high risk of heart disease – Scientists from the University of Warwick have discovered why a newly found form of cholesterol seems to be ‘ultra-bad’, leading to increased risk of heart disease. The discovery could lead to new treatments to prevent heart disease particularly in people with type 2 diabetes and the elderly.
Eggs are now naturally lower in cholesterol — New study shows large eggs are 14 percent lower in cholesterol and 64 percent higher in vitamin D – Eggs are lower in cholesterol than previously thought, according to new nutrition data from the United States Department of Agriculture’s Agricultural Research Service (USDA-ARS).
Statins: Benefits questionable in low-risk patients – There is not enough evidence to recommend the widespread use of statins in people with no previous history of heart disease, according to a new Cochrane Systematic Review.
Adopting Healthy Habits in Youth Associated With More Favorable Cholesterol Levels in Early Adulthood – Lifestyle changes between childhood and adulthood appear associated with whether an individual will maintain, improve or develop high-risk cholesterol levels.
Compounds in nonstick cookware may be associated with elevated cholesterol in children and teens – Children and teens with higher blood levels of chemicals used in the production of non-stick cookware and waterproof fabrics appear more likely to have elevated total and LDL cholesterol levels.
Scientists identify 95 genetic variants associated with cholesterol, triglycerides – Researchers have discovered or confirmed 95 regions of the human genome where genetic variants are associated with blood cholesterol and triglyceride levels, which are major indicators of heart disease risk.
More ‘good’ cholesterol is not always good for your health — HDL cholesterol can transform from good to bad actor in heart-disease process
– We’ve all heard about the importance of raising HDL, or the so-called “good” cholesterol, and lowering LDL, or “bad” cholesterol, to improve heart health. While we’ve come to assume HDL cholesterol is an inherently good thing, a new study shows that for a certain group of patients, this is not always the case.