Intensive statin therapy increases risk of diabetes

Intensive-Dose Statin Therapy Associated With Increased Risk of Diabetes – Use of intensive-dose statin therapy compared with moderate-dose statin therapy was associated with a higher incidence of new-onset diabetes. An analysis of data from previously published studies indicates that intensive-dose statin therapy is associated with an increased risk of new-onset diabetes compared with moderate-dose therapy, according to a study in the recent issue of JAMA.

New safety recommendations for high dose 80 mg simvastatin

FDA announces new safety recommendations for high-dose simvastatin — Increased risk of muscle injury cited – Patients taking simvastatin 80 mg daily had an increased risk of muscle injury. The risk of muscle injury is highest during the first year of treatment with the 80 mg dose of simvastatin, and is frequently associated with a genetic predisposition for simvastatin-related muscle injury or myopathy.

New form of cholesterol revealed in people at high risk of heart disease

Super-sticky ‘ultra-bad’ cholesterol revealed in people at high risk of heart disease – Scientists from the University of Warwick have discovered why a newly found form of cholesterol seems to be ‘ultra-bad’, leading to increased risk of heart disease. The discovery could lead to new treatments to prevent heart disease particularly in people with type 2 diabetes and the elderly.

More good cholesterol is not always good for health

More ‘good’ cholesterol is not always good for your health — HDL cholesterol can transform from good to bad actor in heart-disease process
– We’ve all heard about the importance of raising HDL, or the so-called “good” cholesterol, and lowering LDL, or “bad” cholesterol, to improve heart health. While we’ve come to assume HDL cholesterol is an inherently good thing, a new study shows that for a certain group of patients, this is not always the case.

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