Endurance exercise improves brain health

Scientists identify protein linking exercise to brain health – A protein that is increased by endurance exercise has been isolated and given to non-exercising mice, in which it turned on genes that promote brain health and encourage the growth of new nerves involved in learning and memory.

Darbepoetin alfa does not improve health of anemic heart failure patients

Cleveland Clinic research shows anemia drug does not improve health of anemic heart failure patients — Phase 3 findings published in NEJM provide answers about treatment with darbepoetin alfa – Researchers from Cleveland Clinic and Sweden-based Sahlgrenska University Hospital have found that a commonly used drug to treat anemia in heart failure patients – darbepoetin alfa – does not improve patients’ health, nor does it reduce their risk of death from heart failure.

Anti aging drug may be available within five years

Anti-aging drug breakthrough — potential to prevent age-related diseases and extend lifespans – Drugs that combat ageing may be available within five years, following landmark work led by an Australian researcher. The study finally proves that a single anti-ageing enzyme in the body can be targeted, with the potential to prevent age-related diseases and extend lifespans.

Alcohol helps accelerate brains of heavy drinkers

Enhanced brain acetate metabolism may reward heavy drinkers – Increased brain uptake and oxidation of acetate in heavy drinkers – In addition to its well-known effects on the CNS, alcohol consumption has a significant impact on metabolism. After consumption, the body rapidly begins converting ethanol to acetate, which can serve as an energy source for the brain and other organs.

Link between metabolism and breast cancer

NIH scientists identify molecular link between metabolism and breast cancer – A protein associated with conditions of metabolic imbalance, such as diabetes and obesity, may play a role in the development of aggressive forms of breast cancer, according to new findings by researchers at the National Cancer Institute (NCI).

Kynamro approved to treat inherited cholesterol disorder

US FDA approves new orphan drug Kynamro to treat inherited cholesterol disorder – Kynamro – mipomersen sodium – injection approved as an addition to lipid-lowering medications and diet to treat patients with a rare type of high cholesterol called homozygous familial hypercholesterolemia (HoFH). Kynamro is approved by the U.S. Food and Drug Administration.

3 new drugs approved for type 2 diabetes in US

US FDA approves three new drug treatments for type 2 diabetes – Nesina, Kazano, and Oseni – The U.S. Food and Drug Administration approved three new related products for use with diet and exercise to improve blood sugar control in adults with type 2 diabetes: Nesina (alogliptin) tablets, Kazano (alogliptin and metformin hydrochloride) tablets, and Oseni (alogliptin and pioglitazone) tablets.

Grapefruit and medication interactions increasing

Grapefruit?medication interactions increasing — Grapefruit juice can be dangerous for people on certain medications – Grapefruit juice can be dangerous for people on certain medications. The potential of drug interactions with grapefruit juice has been out there a long time, but most people just aren’t aware of it.

Secondary osteoporosis – treat the cause of osteoporosis first

Secondary osteoporosis: More than what meets the eye! – An SGH study has revealed that considering all osteoporotic patients as having simple osteoporosis and treating all of them alike by putting them on potent long term medication without finding out the cause of their osteoporosis may be ineffective and in most cases downright harmful.

Obesity may lead to impaired brain function

Obesity and metabolic syndrome associated with impaired brain function in adolescents – Metabolic syndrome (MetS) is associated with cognitive and brain impairments in adolescents and calls for pediatricians to take this into account when considering the early treatment of childhood obesity. As childhood obesity has increased in the U.S., so has the prevalence of metabolic syndrome ? a constellation of three or more of five defined health problems, including abdominal obesity, low HDL (good cholesterol), high triglycerides, high blood pressure and pre-diabetic insulin resistance.

Health Newstrack