Metabolism Archives

Alarm clock gene responsible for wake up every morning

‘Alarm clock’ gene explains wake-up function of biological clock — Finding promising insight into sleeplessness, aging and chronic illness, such as diabetes and cancer – Ever wondered why you wake up in the morning – even when the alarm clock isn’t making jarring noises? Wonder no more. Researchers at the Salk Institute for Biological Studies have identified a new component of the biological clock, a gene responsible for starting the clock from its restful state every morning.

29 new genetic variants linked to multiple sclerosis

Multiple sclerosis research doubles number of genes associated with the disease — Critical insight provided into the disease mechanisms behind multiple sclerosis – Scientists have identified 29 new genetic variants linked to multiple sclerosis, providing key insights into the biology of a very debilitating neurological disease. Many of the genes implicated in the study are relevant to the immune system, shedding light onto the immunological pathways that underlie the development of multiple sclerosis.

Increasing muscle mass may lower diabetes risk

Increased muscle mass may lower risk of pre-diabetes — Study shows building muscle can lower person’s risk of insulin resistance – The greater an individual’s total muscle mass, the lower the person’s risk of having insulin resistance, the major precursor of type 2 diabetes, revealed by researchers in a recent study accepted for publication in The Endocrine Society’s Journal of Clinical Endocrinology & Metabolism (JCEM).

Lower calorie foods purchased in restaurants contain more calories than listed

Nutrition researchers examine restaurants’ calorie counts — New study suggests lower calorie foods purchased in restaurants contain more calories than listed – Disclosing the calories in restaurant foods to customers holds promise as a strategy to lower the nation’s obesity rate. However, a new study of food items from national chain restaurants found that while stated calories on restaurant menus and websites were accurate on average, 19% of individual samples differed from laboratory measurements by more than 100 calories and lower calorie foods tended to contain more than listed.

Daily intake of Red wine resveratrol good for people with sedentary lifestyles

Red wine: Exercise in a bottle? — New research in the FASEB Journal suggests that a daily intake of resveratrol prevents the ill effects of simulated weightlessness on muscle and bone metabolism – Resveratrol may be able to prevent the deleterious consequences of sedentary behaviors in humans. Researchers revealed that a daily intake of resveratrol prevents the ill effects of simulated weightlessness on muscle and bone metabolism.

New safety recommendations for high dose 80 mg simvastatin

FDA announces new safety recommendations for high-dose simvastatin — Increased risk of muscle injury cited – Patients taking simvastatin 80 mg daily had an increased risk of muscle injury. The risk of muscle injury is highest during the first year of treatment with the 80 mg dose of simvastatin, and is frequently associated with a genetic predisposition for simvastatin-related muscle injury or myopathy.

Gene variation linked to infertility in women

Gene variation linked to infertility in women, study finds — Altered gene involved in both faulty cholesterol regulation and pregnancy hormone production – A variation in a gene involved in regulating cholesterol in the bloodstream also appears to affect progesterone production in women, making it a likely culprit in a substantial number of cases of their infertility, a new study from Johns Hopkins researchers suggests.

How breast cancer cells adapt to environmental stress

Cancer scientists discover new way breast cancer cells adapt to environmental stress – An international research team led by Dr. Tak Mak, Director, The Campbell Family Institute for Breast Cancer Research at Princess Margaret Hospital (PMH), has discovered a new aspect of “metabolic transformation”, the process whereby tumour cells adapt and survive under conditions that would kill normal cells.

People who go to bed late and sleep late eat more fast food and weigh more

Night owls at risk for weight gain and bad diet — People who go to bed late and sleep late eat more fast food and weigh more – Staying up late every night and sleeping in is a habit that could put you at risk for gaining weight. People who go to bed late and sleep late eat more calories in the evening, more fast food, fewer fruits and vegetables and weigh more than people who go to sleep earlier and wake up earlier.

Turning bad fat into good – A future treatment for obesity

Turning ‘bad’ fat into ‘good’: A future treatment for obesity? — Johns Hopkins researchers transform inert white fat into brown fat to burn off calories and weight – By knocking down the expression of a protein in rat brains known to stimulate eating, Johns Hopkins researchers say they not only reduced the animals’ calorie intake and weight, but also transformed their fat into a type that burns off more energy. The finding could lead to better obesity treatments for humans, the scientists report.

Increased metabolic rate may lead to accelerated aging

Increased metabolic rate may lead to accelerated aging — Findings from new study may explain why low-calorie diets are beneficial for human health – A recent study accepted for publication in The Endocrine Society’s Journal of Clinical Endocrinology & Metabolism (JCEM) found that higher metabolic rates predict early natural mortality, indicating that higher energy turnover may accelerate aging in humans.

Bariatric surgery better than dieting for glucose control

Bariatric surgery better than dieting for glucose control – Researchers have uncovered a new clue for why bariatric surgery is more effective than dietary remedies alone at controlling glucose levels. The study conducted at Duke University Medical Center and St. Luke’s and Roosevelt Hospital Center, Columbia University.