Designing an effective test to detect ovarian cancer

Ovarian cancer tests flawed, in need of new design, says Stanford study — Tiny early stage ovarian tumors define early detection challenge. – Current diagnostic tests for ovarian cancer are woefully ineffective for early detection of the disease, say researchers at Stanford University School of Medicine.

Hormone therapy may increase ovarian cancer risk

Regardless of the duration of use, the formulation, estrogen dose, regimen, progestin type, and route of administration, hormone therapy was associated with an increased risk of ovarian cancer. – Compared with women who have never taken hormone therapy, those who currently take it or who have taken it in the past are at increased risk of ovarian cancer.

Routine MRI scan to evaluate breast cancer is challenged

Study challenges routine use of MRI scans to evaluate breast cancer — Test is linked to delays in treatment, increase in mastectomy rates. – Women with newly diagnosed breast cancer who receive a breast MRI are more likely to receive a mastectomy after their diagnosis and may face delays in starting treatment, revealed by researchers.

Genetic code mistake causes ovarian cancer

Found: 1 in 3 billion — The spelling mistake in the genetic code that causes a type of ovarian cancer. – Eureka! Vancouver scientists from the Ovarian Cancer Research (OvCaRe) Program at BC Cancer Agency and Vancouver Coastal Health Research Institute have discovered that there appears to be a single spelling mistake in the genetic code of granulosa cell tumours, a rare and often untreatable form of ovarian cancer.

Stem cell protein LIN28 offers a new cancer target

LIN28, which maintains cell ‘stemness,’ is abundant in advanced cancers and transforms cells to cancerous state – A protein abundant in embryonic stem cells is now shown to be important in cancer, and offers a possible new target for drug development, report researchers from the Stem Cell Program at Children’s Hospital Boston.

Genetic marker predicts early onset of prostate cancer

Genetic marker may predict early onset of prostate cancer – Fox Chase Cancer Center researchers have identified a genetic marker that is associated with an earlier onset of prostate cancer in Caucasian men who have a family history of prostate cancer. If the data are confirmed, the marker may help clinicians personalize prostate cancer screening.

AMP joins ACLU to challenge BRCA gene patents

AMP joins ACLU to challenge BRCA gene patents

Suit charges that Myriad Genetics BRCA1 and BRCA2 patents interfere with the free flow of information and knowledge in violation of the First Amendment and that human genes are ‘products of nature’ that cannot be patented. – The Association for Molecular Pathology (AMP) announced that it is working with the American Civil Liberties Union (ACLU) and the Public Patent Foundation to bring a lawsuit charging that patents on two human genes associated with breast and ovarian cancer are unconstitutional and should be invalidated.

$51 million for cancer research in US

American Cancer Society awards 143 research grants to investigators at 83 institutions nationwide. Grants total more than $51 million in the second of two cycles for 2009. – The American Cancer Society, the largest non-government, not-for-profit funding source of cancer research in the United States, has awarded 143 national research and training grants totaling more than $51 million in the second of two grant cycles for 2009. The grants go into effect beginning July 1, 2009.

Blood & ultrasound can diagnose ovarian cancer early

Ovarian cancer screening would be feasible in primary care, according to the early results of a major Department of Health, UK funded analysis. – Blood test combined with ultrasound scan can diagnose ovarian cancer (gynecological cancer) early in postmenopausal women, almost 2 years earlier than normal, reported by the British researchers in the Lancet.

Women with BRCA mutation most likely to undergo mastectomy

Women with BRCA mutation, or worry, most likely to undergo prophylactic mastectomy. Patients’ fear should be strongly considered when counseling women at high risk for breast cancer. – Women at increased risk for breast cancer because of the genetic BRCA mutations are more likely to think a prophylactic mastectomy is the best way to reduce their risk for the disease, compared to other women who are at high risk, according to researchers at The University of Texas M. D. Anderson Cancer Center.

Fertility drugs do not increase ovarian cancer risk

No convincing association is found between use of fertility drugs and risk of ovarian cancer, according to a new study. – The use of fertility drugs does not increase a woman’s risk of developing ovarian cancer, finds a large study from Danish researchers published on bmj.com.

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