Ovarian Cancer or Cancer of the ovary is a disease in which cancer (malignant) cells are found in the ovary. Approximately 25,000 women in the United States are diagnosed with this disease each year.
Breast cancer patients with BRCA mutations 4 times more likely to get cancer in opposite breast – Women with breast cancer before age 55 who carry an inherited mutation in the breast cancer susceptibility genes BRCA1 or BRCA2 are four times more likely to develop cancer in the breast opposite, or contralateral, to their initial tumor as compared to breast cancer patients without these genetic defects.
Federal District Court Rules Isolated DNA Claims are Not Patentable — Myriad to Appeal Decision to the Federal Circuit Court of Appeals – A federal judge on Monday struck down patents on two genes — BRCA1 and BRCA2 — linked to breast and ovarian cancer. Shares of Myriad Genetics (MYGN.O) fell as much as 7 percent, a day after the ruling.
Symptoms have little value for early detection of ovarian cancer – Use of symptoms to trigger a medical evaluation for ovarian cancer does not appear to detect early-stage ovarian cancer earlier and would likely result in diagnosis in only 1 out of 100 women in the general population with such symptoms, revealed in an article.
Assessing lead time of selected ovarian cancer biomarkers – Concentrations of the biomarkers CA125, human epididymis protein 4 (HE4), and mesothelin began to rise 3 years before clinical diagnosis of ovarian cancer, according to a new study published online December 30 in the Journal of the National Cancer Institute.
Women often opt to surgically remove their breasts, ovaries to reduce cancer risk – Many women at high risk for breast or ovarian cancer are choosing to undergo surgery as a precautionary measure to decrease their cancer risk, revealed by US researchers.
Ovarian cancer tests flawed, in need of new design, says Stanford study — Tiny early stage ovarian tumors define early detection challenge. – Current diagnostic tests for ovarian cancer are woefully ineffective for early detection of the disease, say researchers at Stanford University School of Medicine.
Regardless of the duration of use, the formulation, estrogen dose, regimen, progestin type, and route of administration, hormone therapy was associated with an increased risk of ovarian cancer. – Compared with women who have never taken hormone therapy, those who currently take it or who have taken it in the past are at increased risk of ovarian cancer.
Study challenges routine use of MRI scans to evaluate breast cancer — Test is linked to delays in treatment, increase in mastectomy rates. – Women with newly diagnosed breast cancer who receive a breast MRI are more likely to receive a mastectomy after their diagnosis and may face delays in starting treatment, revealed by researchers.
Found: 1 in 3 billion — The spelling mistake in the genetic code that causes a type of ovarian cancer. – Eureka! Vancouver scientists from the Ovarian Cancer Research (OvCaRe) Program at BC Cancer Agency and Vancouver Coastal Health Research Institute have discovered that there appears to be a single spelling mistake in the genetic code of granulosa cell tumours, a rare and often untreatable form of ovarian cancer.
LIN28, which maintains cell ‘stemness,’ is abundant in advanced cancers and transforms cells to cancerous state – A protein abundant in embryonic stem cells is now shown to be important in cancer, and offers a possible new target for drug development, report researchers from the Stem Cell Program at Children’s Hospital Boston.
